Treating hypertension with black-jack extract

Wednesday, September 05, 2018 by

Research has shown that black-jack (Bidens pilosa) can help improve symptoms of hypertension. The study, published in the journal BMC Complementary and Alternative Medicine, looked at the effects of ethylene acetate extract of black-jack leaves on L-NAME-induced (a non-specific nitric oxide inhibitor) hypertension in mice.

  • Researchers from the University of Yaounde I in Cameroon induced hypertension by giving L-NAME to mice.
  • At the same time, some mice were orally given 75 milligrams per kilogram (mg/kg) of black-jack leaf ethylene acetate extract every day, 150 mg/kg of black-jack leaf ethylene acetate extract per day, or 25 mg/kg of losartan daily. The treatment lasted for four weeks.
  • At the end of the treatment, researchers recorded the hemodynamic parameters.
  • They also assessed the effects of the extract on lipid profile, kidney and liver functions, and oxidative stress markers.
  • Results revealed that the administration of black-jack leaf ethylene acetate extract prevented hypertension induced by L-NAME without compromising the heart rate.
  • The study also confirms that black-jack can normalize lipid profile, fight against oxidative stress and cell damage in liver and kidney, and enhance endothelial function in hypertensive animal models.
  • These benefits of black-jack may be attributed to the presence of flavonoids like quercetin.

Overall, the findings of the study proved that black-jack leaf extract contains antihypertensive and antioxidative properties.

Read the full text of the study at this link.

To read more stories on preventing heart disease, visit HeartDisease.news today.

Journal Reference:

Bilanda DC, Dzeufiet PDD, Kouakep L, Aboubakar BFO, Tedong L, Kamtchouing P, Dimo T. BIDENS PILOSA ETHYLENE ACETATE EXTRACT CAN PROTECT AGAINST L-NAME-INDUCED HYPERTENSION ON RATS. BMC Complementary and Alternative Medicine. 10 October 2017; 17(479). DOI: 10.1186/s12906-017-1972-0



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